Active Ingredients

• Irbesartan 300 mg
• Hydrochlorothiazide 25 mg

Dosage Form:

Film-Coated Tablets

Therapeutic Class

• Dual-Action Antihypertensive Combination (ARBs + Thiazide Diuretic)

Dosage

• Maximum Control (Uncontrolled on 300 mg / 12.5 mg): Escalate to IRBADOR PLUS 300 mg / 25 mg once daily.

Indications

1. Treatment of Essential Hypertension
2. Flexible Step-Up Therapy: Ideal for patients requiring higher dose titration (up to 300 mg / 25 mg) to reach stringent target blood pressure goals.

Key Benefits

• Maximum Synergistic Efficacy: Higher strength combinations (300 mg / 25 mg) deliver potent, additive blood pressure reduction for severe or treatment-resistant hypertensive cases.
• Comprehensive Strength Flexibility: Offers three tailored dose combinations (150/12.5 mg, 300/12.5 mg, and 300/25 mg), allowing precise dose titration according to individual patient clinical needs.
• Sustained 24-Hour BP Control: Maintains smooth, consistent blood pressure control over a full 24-hour cycle with single daily dosing, preventing early morning BP surges.
• Optimized Tolerability Profile: Irbesartan helps attenuate diuretic-induced metabolic alterations (such as hypokalemia and uric acid changes), preserving safety at higher dose levels.